Your U.S. Order Over $50 Ships Free!
Cart 0

Petsmile by Supersmile - Professional Pet Toothpaste 4.2 oz, Choose from 3 Flavors, 2 for $46 / 3 for $63, Shipping is Free!

$ 25.00

Get any 2 Tubes for $46
Get any 3 Tubes for $63
(Prices include Shipping)

Product Brief:

  • Note: rather than up price, Petsmile reduced size to 4.2 oz vs. previous 4.5 oz
  • Produced in an FDA registered facility approved for the manufacture of OTC pharmaceutical products
  • Not 100% natural, but we can’t find an all-natural product as effective as this one. We accepted this product because the synthetic ingredients are known to be safe for Pets & People - see ingredient list below for details
  • Just squeeze Petsmile on your finger and swipe across your pet's teeth. Once your pet's saliva mixes with Petsmile, plaque inhibition begins
  • The quick-dissolving formula is flavored with natural London Broil beef, Rotisserie Chicken, or Say Cheese flavor that dogs & cats love. The results are clean, healthy teeth & fresh breath!  

The Importance of Pet Oral Care

Besides nutrition, oral care is the most critical issue to your pet's health & longevity. Most of us barely have time to brush our own teeth, let alone our pet's teeth! But Petsmile requires no brushing so it's very easy to use (video). Cats & dogs LOVE the  flavors & using 2 to 3 times weekly will prevent your pet from developing plaque & avoid devastating, costly diseases resulting from poor oral health.

Full disclaimer: Petsmile is made with safe, food grade ingredients, but it's not 100% natural. There ARE a few chemicals at the end of the ingredient list. So why would we still accept this product & use it on our own pets? Because we have lost beloved pets to the ravaging effects caused by periodontal disease (PD) & its complications. So our approach to oral health is analogous to people with chronic diseases who must take a limited amount of synthetic medication to survive. We choose a more balanced approach in the area of oral care because:

  1. Oral care that inhibits plaque is critical to our beloved pets' long term health
  2. We've been unable to find or create a completely natural oral product that really works well
  3. Since this product is fast & easy to use & pets love it, we're hoping more people will actually start taking action on pet oral care, especially since this product eliminates the usual oral care drama associated with pets

Made for Pets, but Works for Humans Too!

Petsmile contains no flouride, parabens, silica, sulfates or dyes. Human toothpastes are toxic to pets, but Petsmile is safe & effective for humans too! We tested the London Broil beef, Rotisserie Chicken, and Say Cheese flavors on ourselves - reminds us of tart yogurt. So if you like "tangy" over "minty", it's great for you too! The formula provides the same benefits as Supersmile (for humans) with a tangier taste (Petsmile is fine for pets & humans; but Supersmile is NOT for pets).

Where's the Science - Why is Oral Care so Critical to Pet Health?

When we skip regular pet dental care, food & bacteria accumulate into plaque buildup on teeth. Plaque transforms into tartar, causing gum inflammation called "gingivitis" which can lead to Periodontal Disease (PD). Left untreated, gingivitis can develop into PD, which is an infection in gums, teeth & all surrounding tissue. PD results from poor (or no) dental hygiene. PD is the most common major health problem of cats & dogs, affecting the teeth, mouth & entire body. Skipping this essential task puts your pet's health, longevity & well-being at risk.

The body’s immune system cannot control or reverse the infection. Left untreated, PD can lead to major complications including pain, tooth loss, bad breath, lethargy, blood poisoning, decreased lifespan & premature death. PD is also thought to contribute to - and increase risk of - serious diseases like autoimmune diseases, diabetes, heart / lung / kidney infections, cancer & heart failure. As if that's not enough, the prognosis may not be good and the cost to treat infections & other serious conditions can add up to a lot of unwanted expense.  'Nuff said - you get the picture.

The good news is PD is preventable with regular home use of Petsmile. The active ingredient Calprox is safe & gentle on teeth, but powerful in preventing plaque buildup. Petsmile's trademarked Calprox is CLINICALLY proven to safely & gently prevent plaque buildup, fight bacteria, help diminish bad breath & whiten teeth. Plus it does not contain abrasive silicas, which abrade plaque AND destroy non-repleneshable tooth enamel. Petsmile inhibits plaque growth, with no damage to your pet's tooth enamel.

Remember the cycle:

Phase 1) Food & bacteria accumulate on teeth & gumline
Phase 2) The teeth accumulate plaque
Phase 3) Plaque buildup becomes tartar, causing gum irritation
Phase 4) Inflammation of gums occurs (gingivitis)
Phase 5) Periodontal Disease

Insert Petsmile between Phases 1 & 2 above and stop the cycle.

What if my Pet Won't Let me Use a Toothbrush?

Petsmile makes it convenient & quick - use 2-3 times weekly & no toothbrush is required! Once your pet's saliva mixes with Petsmile, plaque inhibition begins. The quick-dissolving formula is flavored with a London Broil beef, Rotisserie Chicken, or Say Cheese flavor dogs & cats love. The results are clean, healthy teeth & fresh breath!

Some pets just don't like toothbrushes; with Petsmile you can apply with your finger or a cotton swab. Just apply a pearl size to the end of your finger or swab & spread evenly around your pet's teeth. Toothbrush diehards can continue using a toothbrush, but it is not necessary. Calprox's plaque blasting system is activated by saliva so when your licks Petsmile around the mouth, it starts working - so you can even apply the paste to your pet's favorite toy too!

Does Petsmile remove the Discolored Buildup on My Pet's Teeth?

No. Discolored buildup on teeth is tartar buildup that has to be removed by a veterinarian through a professional teeth cleaning. Petsmile is a plaque inhibitor, NOT a tartar remover. So once existing tartar is removed, then your pet is ready for a Petsmile "fresh start"! Like all products carried at Really Natural, Petsmile is safe AND effective for humans too!


Apply a pearl size amount to the end of your finger or swab to spread evenly around your pet's teeth. Let your pet lick Petsmile around the mouth.  Safe for kittens, puppies, cats & dogs, so start your pets at a young age to help them learn the habit of regular dental hygiene. See how easy the product is to use - just swipe over pet teeth and gums with your finger: watch video.


Deionized Water: Ion-free water
Glycerin: Kosher vegetable glycerin provides moisture to toothpaste
Citric acid: Naturally occurring acid from citrus fruit to reduce tartar & remove stains
Dicalcium Phosphate Dihydrate: Restores calcium to teeth
Calprox: Proprietary, silica-free, whitening ingredient that dissolves stains & cleans teeth with no enamel abrasion
Cellulose Gum: Natural thickener to make toothpaste creamy
Urea Peroxide: Tooth whitener
Carbopol 934P: Toothpaste thickener
Potassium Hydroxide: Neutralizes acidity to help prevent tooth decay
Natural London Broil Beef or Rotisserie Chicken Flavor
Phosphoric Acid: Stabilizes formula
Sodium Benzoate: Neutralizer
EDTA: Chelating agent that helps fight plaque & the protein pellicle that attracts stains & plaque
Cetyl Pyridinium Chloride: Contains anti-microbials to fight plaque & plaque build up


Customer Reviews

Based on 89 reviews
Bring back Savory Duck!

My cat loved the Savory duck flavour but I can find it nowhere now. I tried London Broil - £30 down the drain. I am reluctant to risk another 30 to try Rotisserie Chicken. I know he will not eat cheese so that flavour is no good. What a shame that I found a product that worked so well, only to have it disappear.

Thanks for sharing your feedback, Lisa. We're sorry your cat did not like London Broil. But since his favorite Savory Duck flavor was discontinued, he might also like Rotisserie Chicken, since both are poultry flavors. Thanks for being a customer!

Happy pups!

My pups are so happy to have received this. I also received a personalized note and some treats for them. I was pleasantly surprised. Thank you!!!

Thanks so much for your feedback, Megan - we hope Petsmile works well for your pups and we sure appreciate your business!


Loved how they personalized the order with dog treats and a special thank you note!

Thanks so much for sharing your experience, Lucia - we hope Petsmile works well for you! Thanks for being a customer!

Best toothpaste and customer service!

Quick shipping and arrival, always a handwritten personal note in the package. These folks are the best. And the Petsmile toothpaste is the best I have ever used, my female mini schnauzer loves the taste and loves to have her teeth brushed with it. Eliminates tarter and gives her fresh breath.

Thanks so much for taking the time to review,Lynn - we're happy Petsmile is working well for your schnauzer girl! Thanks for being a customer!

Puppy loves Petsmile!

My puppy loves the toothpaste!

Thanks so much for sharing, Greg - we're happy your puppy is loving Petsmile! Thanks for being a customer!

Share this Product